Ensaios clínicos após o VIOXX/ Clinical trials after VIOXX.
Texto de MD Roth-Cline na Circulation sobre ensaios clínicos e toxicidade de medicamentos.

Text by MD Roth-Cline in Circulation on clinical trials and drug toxicity.

"more people would be harmed by delaying dissemination of all drugs for a year than by releasing a small number of drugs with undesirable risk-benefit profiles"

"the most direct approach is to add a second criterion to early termination guidelines"